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Pharmacokinetic Properties



Molecule Depiction


SMILES

Molecule properties:

Descriptor Value
Molecular Weight 375.871
LogP 4.3172
#Rotatable Bonds 6
#Acceptors 3
#Donors 1
Surface Area 157.952
Property Model Name Predicted Value Unit
Absorption Caco2 1.09 Numeric (log cm/s)
Absorption Water solubility -4.906 Numeric (log mol/L)
Absorption Intestinal absorption (human) 91.125 Numeric (% Absorbed)
Absorption P-glycoprotein substrate No Categorical (Yes/No)
Absorption P-glycoprotein I inhibitor Yes Categorical (Yes/No)
Absorption P-glycoprotein II inhibitor Yes Categorical (Yes/No)