Descriptor | Value |
---|---|
Molecular Weight | 375.871 |
LogP | 4.3172 |
#Rotatable Bonds | 6 |
#Acceptors | 3 |
#Donors | 1 |
Surface Area | 157.952 |
Property | Model Name | Predicted Value | Unit |
---|---|---|---|
Absorption | Caco2 | 1.09 | Numeric (log cm/s) |
Absorption | Water solubility | -4.906 | Numeric (log mol/L) |
Absorption | Intestinal absorption (human) | 91.125 | Numeric (% Absorbed) |
Absorption | P-glycoprotein substrate | No | Categorical (Yes/No) |
Absorption | P-glycoprotein I inhibitor | Yes | Categorical (Yes/No) |
Absorption | P-glycoprotein II inhibitor | Yes | Categorical (Yes/No) |