Results

Predicted Stability Change (ΔΔGStability wt->mt)

-1.67 kcal/mol

(Destabilising)


Reverse Prediction (ΔΔGStability mt->wt)


2.27 kcal/mol (Stabilising)


Mutation Details


Chain: A

Position: 461

Wild-type: H

Mutant: D

Wild-type residue environment


Depth: 2.07 Å

RSA: 0.19 Å3

Phi: -80.7 °

Psi: 133.8 °

Relative bfactor: 3.5

Contacts
Interactions

Clash

VDW

Hydrogen Bond

Ionic

Aromatic

Hydrophobic

Carbonyl

Polar