Chemical respiratory toxicity might cause severe harms to the human body. Therefore, it is necessary to better understand it to identify these potential respiratory toxic compounds in advance. In this context, this endpoint encompasses three main databases to define toxicity or safety in the respiratory system: the PNEUMOTOX database (released on March 09, 2020), the ADReCS database (released on May 15, 2019) and the Hazardous Chemical Information System (released on May 09, 2018). Other papers were also used to determine respiratory toxicity or safety, such as [35], [40], [41], [42], [43] and [44] (see the reference). For this data, toxic compounds comprehend cases where adverse effects on the human respiratory system were identified, whereas safe compounds are those considered as harmless to the respiratory system, including respiratory non-sensitizers and skin non-sensitizers.