Single-Point Mutation
Results
Predicted Affinity Change (ΔΔGAffinity)
-2.019 kcal/mol
(Decreasing affinity)
Mutation Details
Chain: I
Position: 45
Wild-type: LEU
Mutant: GLY
Distance from closest partner: 2.72Å
Interactive Viewer
Interactions
Clash
VDW
Hydrogen Bond
Ionic
Aromatic
Hydrophobic
Carbonyl
Polar
Interactions: Wild-Type x Mutant
Controls
Wild-Type (dashed lines)
Mutant (straight lines)
Carbonyl
Aromatic
Ionic
VDW
Hydrogen bonds
Hydrophobic
Polar Hbond
Clash
Ring-Ring