Single-Point Mutation
Results
Predicted Affinity Change (ΔΔGAffinity wt->mt)
-1.25 kcal/mol
(Decreasing affinity)
Mutation Details
Chain: A
Position: 161
Wild-type: ALA
Mutant: GLY
Ligand Details
ID: 01S
Wild-affinity: 6.72
Interactive Viewer
Interactions
Clash
VDW
Hydrogen Bond
Ionic
Aromatic
Hydrophobic
Carbonyl
Polar
Interactions: Wild-Type x Mutant
Controls
Wild-Type (dashed lines)
Mutant (straight lines)
Carbonyl
Aromatic
Ionic
VDW
Hydrogen bonds
Hydrophobic
Polar
Clash
Node Importance