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Thanks for using AlzDiscovery!

For more details on model development, please check the original paper.

List of Proteins

List of proteins
  • There are 21 Alzheimer's Disease-related proteins available for the users to browse the effect of the mutations leading to diseases.


  • For more information about the protein of interest, please check the introduction from the UniProt website and literature.

Mutation Browser - Details

introduction

1. Here is a short introduction about the protein and how it links to Alzheimer's Disease.

select mutation

2. Use the mouse to hover and browse the mutations based on the wild-type (x-axis) and mutant (y-axis) amino acids.
3. Click to view the residue interaction.
Demo

structure viewer

4. Use the mouse to drag/move/zoom the 3D structure of the wild-type protein.
5. Different colour schemes are available to display more information.
Demo

interaction change

6. A summary of the changes of different types of residue interaction is displayed on a table.
7. Interaction changes are based on the mutation selected.

download

8. Further information is available to download.